Background/Aim.Virological testing is considered to be essential in the management of hepatitis C virus (HCV) infection in order to diagnose infection, and, most importantly, as a quide for treatment decisions and assess the virological response to antiviral therapy.The aim of this study was to determine the rate of a sustained virological response
Differential active site loop conformations mediate promiscuous activities in the lactonase SsoPox.
Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release.These different steps may require different conformational states of the active site that have distinct binding properties.Moreover, the conformational flexibility of the active site mediates alternative, promiscuous functi
Cellular MicroRNA Expression Profile of Chicken Macrophages Infected with Newcastle Disease Virus Vaccine Strain LaSota
Vaccines with live, low-virulence Newcastle disease virus (NDV) strains are still the most accepted prevention and control strategies for combating Newcastle disease (ND), a major viral disease that hampers the development of the poultry industry worldwide.However, the mechanism underlying vaccine-mediated Matching Ugly Sweaters innate cell immune
Eco-Efficient Fiber-Reinforced Preplaced Recycled Aggregate Concrete under Impact Loading
This study explores highly eco-efficient preplaced aggregate concrete mixtures having superior tensile characteristics and impact resistance developed for pavement and infrastructure applications.A fully recycled Cleaning granular skeleton consisting of recycled concrete aggregate and recycled tire rubber granules, and steel wire fibers from scrap
Smooth ROC curve estimation via Bernstein polynomials.
The receiver operating characteristic (ROC) curve is commonly used to evaluate the accuracy of a diagnostic test for classifying observations into two groups.We propose two novel tuning parameters for estimating the ROC curve via Bernstein polynomial smoothing of the empirical ROC curve.The new estimator is very easy to implement with the naturally